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The development of multicomponent reactions (MCR) is the prefered eco-compatible approach to sophisticated molecules of pharmaceutical interest, such as amidines. We elaborated a new MCR to amidines which produces them i... -
We have introduced an original sensing scheme that is based on the aptamer switch from a destabilized, inactive metal-complexed state to a stabilized, active target-bound conformer. The useful features of the strategy we... -
The proliferation of multiresistant bacteria is having an increasing and profound impact on the world. A credible alternative to antibiotics is bacteriophage therapy, which are expected in the near future to form the bas... -
Surface nanopatterning with self-assembled molecules has gained in interest over the last years because of its usefullness in nanotechnology. In here, the natural abilities of a protein to self-assemble in a honeycomb st... -
Bicyclic compounds bearing a quaternary stereogenic center have been obtained using asymmetric intramolecular Buchner reaction with excellent yields and level of enantioselectivity. X-ray crystallography determination of... -
We have developed an enzymatic process that achieves high performance towards the reversible electrochemical CO2-to-CO conversion under mild conditions with low overvoltage. Using an engineered Carbon Monoxide Dehydrogen... -
This publication reports the unprecedented reactivity of a molecular electrocatalyst physiadsorbed on a graphite electrode: a bioinspired Ni(II)Fe(II) complex selectively and catalytically reduces CO2 in acidic aqueous s... -
In targeted DNP, polarizing agents are localized at specific sites of the biomolecular system allowing the development of NMR approaches to improve sensitivity, background suppression for in-cell NMR, access to long-rang... -
The ecological transition requires cheap and abundant electrocatalysts to achieve six key reactions: H2 evolution (HER), H2 oxidation (HOR), CO2 reduction (CO2RR), N2 reduction (NRR), O2 evolution (OER), and O2 reduction... -
In collaboration between two teams of Grenoble, CERMAV & SyMMES, and a Finnish team (Aalto University – Prof. Olli IKKALA), the first ever built linear supramolecular polysaccharide has been obtained. This proof-of-con...
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